Soft Matter
Self-assembly, surfactants, polymers, micelles, and responsive molecular systems.
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Physical Chemistry × Biology
Mohd Sajid Lone, PhD
Postdoctoral Fellow · Indiana University School of Medicine
Exploring how fluorescence, molecular interactions, soft materials, and physical chemistry can be translated into tools for understanding biological systems and disease.
Mohd Sajid Lone
Physical Chemist
Chemical Biology Researcher
Fluorescence & FRET
Energy transfer, photoluminescence, fluorophore interactions, and spectroscopy.
2Molecular Imaging
Photochemical contrast generation and methods for visualizing molecular-scale biology.
3Translational Biosensing
Applying physical-chemistry principles to biological measurement and disease research.
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About Me
From molecular interactions to biological questions
My research background began in physical chemistry, where I studied how molecular organization and local chemical environments control fluorescence, self-assembly, transport, and energy transfer.
Across soft-matter systems, surfactants, polymers, fluorophores, and optoelectronic materials, I have been interested in a common question: how can molecular-scale interactions be converted into useful measurements or functional materials?
My work has since expanded toward biological and translational questions. At Indiana University, I am applying this physical-chemistry perspective to research at the interface of chemistry, biology, and disease, including approaches relevant to type 1 diabetes.
Research
Research Themes
A research path connecting molecular self-assembly, spectroscopy, photophysics, imaging, and biological measurement.
Soft Matter & Molecular Self-Assembly
Investigating how surfactants, polymers, micelles, and mixed molecular systems organize in solution and how that organization controls material properties, solubilization, rheology, transport, and responsive behavior.
Fluorescence & Energy Transfer
Using fluorescence spectroscopy and Förster resonance energy transfer to understand molecular proximity, energy relay, excimer formation, photoluminescence, and environmentally sensitive optical behavior.
Photophysics & Functional Materials
Studying how local molecular structure influences optical and electronic properties in functional materials, including mixed ionic-electronic conductors and related systems.
Molecular Imaging & Contrast Chemistry
Developing and examining photochemical processes that generate imaging contrast, including photosensitized polymerization and molecular-scale approaches for connecting chemical activity with cellular structure.
Drug Delivery & Responsive Systems
Designing and characterizing molecular assemblies capable of responding to environmental signals such as pH, with applications in drug stabilization, controlled release, and functional soft materials.
Physical Chemistry in Biology
Translating expertise in spectroscopy, polymers, electrochemistry, fluorescence, and molecular interactions toward biological sensing and disease-focused research.
Research Journey
A multidisciplinary path
University of Kashmir
Physical Chemistry & Soft Matter
Doctoral and early research focused on surfactant systems, self-assembled nanostructures, FRET, fluorescence spectroscopy, solubilization, responsive materials, and soft-matter chemistry.
University of Utah
Postdoctoral Research · Photophysics & Imaging
Expanded into functional materials, photoluminescence, ion insertion in organic mixed conductors, and photochemical strategies for correlative molecular imaging.
Indiana University School of Medicine
Postdoctoral Fellow · Chemistry × Biology
Current work brings a physical-chemistry toolkit into biological and disease-oriented research, with an emphasis on creating and applying measurement strategies relevant to immune and metabolic disease.
Selected Work
Publications
Selected publications illustrating the progression from soft-matter chemistry and FRET to functional materials and molecular imaging.
2024
Journal of the American Chemical Society
Electron Transfer Drives the Photosensitized Polymerization of Contrast Agents by Flavoprotein Tags for Correlative Microscopy
Mohd Sajid Lone, Olga D. Merino-Chavez, Nathan J. Ricks, and collaborators
View publication →
2024
Advanced Functional Materials
Photoluminescence Probes Ion Insertion into Amorphous and Crystalline Regions of Organic Mixed Conductors
Garrett W. Collins, Mohd Sajid Lone, Seth R. Jackson, and collaborators
View publication →
2021
Soft Matter
Energy Transduction through FRET in Self-Assembled Soft Nanostructures Based on Surfactants/Polymers
Mohd Sajid Lone, Parvaiz Ahmad Bhat, Saima Afzal, Oyais Ahmad Chat, Aijaz Ahmad Dar
View publication →
2019
The Journal of Physical Chemistry B
Broad Spectrum Tunable Photoluminescent Material Based on Cascade Fluorescence Resonance Energy Transfer
Mohd Sajid Lone, Saima Afzal, Oyais Ahmad Chat, Parvaiz Ahmad Bhat, and collaborators
View publication →
2017
ChemistrySelect
A Green pH-Switchable Amino Acid Based Smart Wormlike Micellar System for Efficient and Controlled Drug Delivery
Mohd Sajid Lone, Parvaiz Ahmad Bhat, Rais Ahmad Shah, and collaborators
View publication →
Toolkit
Scientific Expertise
Fluorescence Spectroscopy
Förster Resonance Energy Transfer
Soft Matter
Surfactants
Polymers
Self-Assembly
Photoluminescence
Molecular Imaging
Photophysics
Drug Delivery
Responsive Materials
Electrochemistry
Organic Mixed Conductors
Biosensing
Material Characterization
Current Research Home
Piganelli Laboratory
Indiana University School of Medicine · Indianapolis, Indiana